Fell into a rabbithole remarkably similar to this a while ago.
Synth Host system,Win7, Reaper, Presonus, MIO-10 and MidiSport usb-Midi interfaces and my Teensy usbMIDI project. Everything worked until adding and using the IDE.
From a cold start, Win7, Reaper, Presonus, MIO-10 and MidiSport...