Hi Davidelvig,
I am in a similar boat, moving designs from Teensy 3.5 to Teensy 4.1.
I've tested 3 x Teensy 4.1 boards (1 abused and 2 fresh out the packet), and 2 x Teensy 3.5 (1 abused and 1 fresh out the packet). I measured the current consumption from a CR2032 battery connected to VBAT...