Line level isn't designed to drive 600 ohm loads (no one uses 600 ohm in audio these days) but may be able to (check SGTL5000 datasheet for this). Balanced signal cables are used professionally to avoid any ground loop issues, but with single-ended signalling this is always a risk.Now then, should I use audio transformers on the line input and output signals to perform isolation? While that sounds (ha ha, this must happen a lot when describing things) like a plan, the transformers are likely to limit the bandwidth of the source and output signals to from the audio board which I'd like to avoid. If I were to do so, would I use 600ohm/600ohm audio transformers?