I definitely had some issues with the "Fastest" optimize option and a larger code base of ours. We mainly use the OctoWS2811 library but I had significant issues with some fades between LED colors. Once I switched back to the "Fast" or "Smallest Code" option everything performed as expected. I'm happy to help debug it a little more but I wasn't sure where to start and a colleague of mine needed to get our board out the door so I didn't test much after everything was functional.
To note I tried Arduino 1.6.13, 1.8.1, 18.2 using Teensyduino 1.36
To note I tried Arduino 1.6.13, 1.8.1, 18.2 using Teensyduino 1.36
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