I designed the PCBs for my project around the 2.0, which i'm aware is going away (sooner than I thought). It's interfacing an ADS1115 and a 3rd-party 5-volt UART device.
I am only using 6 pins on the 2.0: Vcc, Gnd, TX1, RX1, SDA, SCL
The UART header only has TX, RX, and Ground
The ADS1115...